GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG
AFXBO-SG,AFNBO-SG + H2O → AFXBO-CG,AFNBO-CG + L-Glu
- Reactome
- R-HSA-5433072
- Compartment
- extracellular region · plasma membrane
- Rhea
- RHEA:59469
Inputs
- AFXBO-SG,AFNBO-SGR-ALL-5490253, extracellular region
- H2OCHEBI:15377, H2O, extracellular region
Outputs
- AFXBO-CG,AFNBO-CGR-ALL-5490235, extracellular region
- L-GluCHEBI:29985, C5H8NO4, extracellular region
Catalysed by
- glutathione gamma-glutamate hydrolase activity of GGT dimers [plasma membrane]EC 3.4.19.13
Literature
- Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney Biochem Biophys Res Commun, 1989
- Human kidney gamma-glutamyl transpeptidase. Catalytic properties, subunit structure, and localization of the gamma-glutamyl binding site on the light subunit J Biol Chem, 1977
- The human gamma-glutamyltransferase gene family Hum Genet, 2008