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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C

AFXBO-C,AFNBO-C + Ac-CoA → CoA-SH + AFXBO-NAC,AFNBO-NAC + H+

Reactome: R-HSA-5433066
Compartment: cytosol
Rhea: RHEA:19214

Inputs

AFXBO-C,AFNBO-CR-ALL-5490231, cytosol
Ac-CoACHEBI:57288, C23H34N7O17P3S, cytosol

Outputs

CoA-SHCHEBI:57287, C21H32N7O16P3S, cytosol
AFXBO-NAC,AFNBO-NACR-ALL-5490236, cytosol
H+CHEBI:15378, H, cytosol

Catalysed by

L-cysteine-S-conjugate N-acetyltransferase activity of unknown NAT [cytosol]EC 2.3.1.80

Literature

Glutathione conjugation and conversion to mercapturic acids can occur as an intrahepatic process J Toxicol Environ Health, 1994