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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

glycine + O2 => glyoxylate + H2O2 + NH4+

Gly + H2O + O2 → glyoxylate + H2O2 + NH4+

Reactome: R-HSA-389821
Compartment: peroxisomal matrix
Rhea: RHEA:11533

Inputs

GlyCHEBI:57305, C2H5NO2, peroxisomal matrix
H2OCHEBI:15377, H2O, peroxisomal matrix
O2CHEBI:15379, O2, peroxisomal matrix

Outputs

glyoxylateCHEBI:36655, C2HO3, peroxisomal matrix
H2O2CHEBI:16240, H2O2, peroxisomal matrix
NH4+CHEBI:28938, H4N, peroxisomal matrix

Catalysed by

D-amino-acid oxidase activity of DAO dimer [peroxisomal matrix]EC 1.4.3.3

glycine + O2 => glyoxylate + H2O2 + NH4+

Inputs

Outputs

Catalysed by

Literature