SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol
ligands of SLC7A5 → ligands of SLC7A5
- Reactome
- R-HSA-352232
- Compartment
- plasma membrane
Inputs
- ligands of SLC7A5R-ALL-352229, extracellular region
Outputs
- ligands of SLC7A5R-ALL-352227, cytosol
Catalysed by
- L-amino acid transmembrane transporter activity of SLC7A5:SLC3A2 [plasma membrane]
Literature
- Human LAT1, a subunit of system L amino acid transporter: molecular cloning and transport function Biochem Biophys Res Commun, 1999
- Identification of a membrane protein, LAT-2, that Co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids J Biol Chem, 1999
- Functional characterization of tyrosine transport in fibroblast cells from healthy controls Neurosci Lett, 2008