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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane

G6P + Pi → G6P + Pi

Reactome: R-HSA-3257122
Compartment: cytosol · endoplasmic reticulum membrane · endoplasmic reticulum lumen
Rhea: RHEA:71537

Inputs

G6PCHEBI:58225, C6H11O9P, cytosol
PiCHEBI:43474, HO4P, endoplasmic reticulum lumen

Outputs

G6PCHEBI:58225, C6H11O9P, endoplasmic reticulum lumen
PiCHEBI:43474, HO4P, cytosol

Catalysed by

glucose 6-phosphate:phosphate antiporter activity of SLC37A1,2 [endoplasmic reticulum membrane]

Literature

SLC37A1 and SLC37A2 are phosphate-linked, glucose-6-phosphate antiporters PLoS ONE, 2011
The SLC37 family of phosphate-linked sugar phosphate antiporters Mol. Aspects Med., 2013