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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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SREBP1A,1C binds the ACACA promoter

SREBP1A,1C dimer + ACACA gene → SREBP1A,1C:ACACA gene

Reactome
R-HSA-2426160
Compartment
nucleoplasm
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • DNA-binding transcription activator activity, RNA polymerase II-specific of SREBP1A,1C dimer [nucleoplasm]

Literature

  1. Sterol regulation of acetyl coenzyme A carboxylase promoter requires two interdependent binding sites for sterol regulatory element binding proteins J Lipid Res, 1997
  2. Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle Physiol Genomics, 2008