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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase

1-3-oxo-THA-CoA + CoA-SH → DHA-CoA + Ac-CoA

Reactome: R-HSA-2066788
Compartment: peroxisomal matrix
Rhea: RHEA:39132

Inputs

1-3-oxo-THA-CoACHEBI:65131, C45H68N7O18P3S, peroxisomal matrix
CoA-SHCHEBI:57287, C21H32N7O16P3S, peroxisomal matrix

Outputs

DHA-CoACHEBI:65132, C43H66N7O17P3S, peroxisomal matrix
Ac-CoACHEBI:57288, C23H34N7O17P3S, peroxisomal matrix

Catalysed by

acetate CoA-transferase activity of ACAA1 [peroxisomal matrix]EC 2.8.3.8; UniProt P09110

Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase

Inputs

Outputs

Catalysed by

Literature