Skip to content
DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
Data
100%

Loading the map…

Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA

THA-CoA + O2 → delta2-THA-CoA + H2O2

Reactome
R-HSA-2066787
Compartment
peroxisomal matrix
Rhea
RHEA:39120

Inputs

Outputs

Catalysed by

  • acyl-CoA oxidase activity of ACOX1 dimer [peroxisomal matrix]EC 1.3.3.6

Literature

  1. Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid J Lipid Res, 1995
  2. Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid J Lipid Res, 2001
  3. Peroxisomal straight-chain Acyl-CoA oxidase and D-bifunctional protein are essential for the retroconversion step in docosahexaenoic acid synthesis J Biol Chem, 2001