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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx)

1-3-oxo-THA-CoA + CoA-SH → DHA-CoA + propionyl CoA

Reactome
R-HSA-2066781
Compartment
peroxisomal matrix
Rhea
None recorded

Inputs

  • 1-3-oxo-THA-CoACHEBI:65131, C45H68N7O18P3S, peroxisomal matrix
  • CoA-SHCHEBI:57287, C21H32N7O16P3S, peroxisomal matrix

Outputs

  • DHA-CoACHEBI:65132, C43H66N7O17P3S, peroxisomal matrix
  • propionyl CoACHEBI:57392, C24H36N7O17P3S, peroxisomal matrix

Catalysed by

Literature

  1. Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid J Lipid Res, 1995
  2. Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid J Lipid Res, 2001