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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

SREBP1A,1C,2 binds Importin beta-1

SREBP1A,1C,2 dimer + KPNB1 → SREBP1A,1C,2:Importin beta-1

Reactome: R-HSA-2065550
Compartment: cytosol
Rhea: None recorded

Inputs

SREBP1A,1C,2 dimerR-HSA-2065548, cytosol
KPNB1R-HSA-180733, cytosol

Outputs

SREBP1A,1C,2:Importin beta-1R-HSA-2065556, cytosol

Catalysed by

nuclear import signal receptor activity of KPNB1 [cytosol]UniProt Q14974

SREBP1A,1C,2 binds Importin beta-1

Inputs

Outputs

Catalysed by

Literature