Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Cytosolic folate export across the plasma membrane

FOLA + H+ → FOLA + H+

Reactome: R-HSA-200646
Compartment: plasma membrane
Rhea: RHEA:70159

Inputs

FOLACHEBI:62501, C19H17N7O6, cytosol
H+CHEBI:15378, H, cytosol

Outputs

FOLACHEBI:62501, C19H17N7O6, extracellular region
H+CHEBI:15378, H, extracellular region

Catalysed by

folic acid:proton symporter activity of SLC46A1 [plasma membrane]UniProt Q96NT5

Cytosolic folate export across the plasma membrane

Inputs

Outputs

Catalysed by

Literature