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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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SLC7A4 exchanges G6P for Pi across the ER membrane

G6P + Pi → G6P + Pi

Reactome
R-HSA-198513
Compartment
cytosol · endoplasmic reticulum membrane · endoplasmic reticulum lumen
Rhea
RHEA:71537

Inputs

Outputs

Catalysed by

  • glucose 6-phosphate:phosphate antiporter activity of SLC37A4 [endoplasmic reticulum membrane]UniProt O43826

Literature

  1. The glucose-6-phosphate transporter is a phosphate-linked antiporter deficient in glycogen storage disease type Ib and Ic FASEB J., 2008
  2. Sequence of a putative glucose 6-phosphate translocase, mutated in glycogen storage disease type Ib FEBS Lett, 1997
  3. A gene on chromosome 11q23 coding for a putative glucose- 6-phosphate translocase is mutated in glycogen-storage disease types Ib and Ic Am. J. Hum. Genet., 1998