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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Efflux of Glc from the endoplasmic reticulum

Glc → Glc

Reactome: R-HSA-198458
Compartment: endoplasmic reticulum lumen · endoplasmic reticulum membrane · cytosol · plasma membrane · extracellular region
Rhea: RHEA:60376

Inputs

GlcCHEBI:4167, C6H12O6, endoplasmic reticulum lumen

Outputs

GlcCHEBI:4167, C6H12O6, extracellular region

Literature

Evidence for high-capacity bidirectional glucose transport across the endoplasmic reticulum membrane by genetically encoded fluoresence resonance energy transfer nanosensors Mol Cell Biol, 2005
Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway Am J Physiol Endocrinol Metab, 2002
The glucose-6-phosphatase system Biochem J, 2002