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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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DHF is reduced to tetrahydrofolate (THF)

DHF + NADPH + H+ → THF + NADP+

Reactome
R-HSA-197972
Compartment
cytosol
Rhea
RHEA:15011

Inputs

Outputs

Catalysed by

Literature

  1. The functional human dihydrofolate reductase gene J Biol Chem, 1984
  2. Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate Biochemistry, 1990