Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

ABCC3 transports bile salts from cytosol to extracellular region

bile salts and acids + ATP → ADP + Pi + bile salts and acids

Reactome: R-HSA-194153
Compartment: plasma membrane · cytosol · extracellular region
Rhea: RHEA:50056, RHEA:50052, RHEA:50060, RHEA:50064, RHEA:50048

Inputs

bile salts and acidsR-ALL-194156, cytosol
ATPCHEBI:30616, C10H12N5O13P3, cytosol

Outputs

ADPCHEBI:456216, C10H12N5O10P2, cytosol
PiCHEBI:43474, HO4P, cytosol
bile salts and acidsR-ALL-192483, extracellular region

Catalysed by

ABC-type bile acid transporter activity of ABCC3 [plasma membrane]UniProt O15438

ABCC3 transports bile salts from cytosol to extracellular region

Inputs

Outputs

Catalysed by

Literature