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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix

5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol → 5bCHOL3a,7a,12a,27-tetrol

Reactome: R-HSA-193832
Compartment: mitochondrial inner membrane
Rhea: None recorded

Inputs

5beta-cholestan-3alpha,7alpha,12alpha,27-tetrolCHEBI:17278, C27H48O4, cytosol

Outputs

5bCHOL3a,7a,12a,27-tetrolCHEBI:17278, C27H48O4, mitochondrial matrix

Catalysed by

alcohol transmembrane transporter activity of unknown START protein [mitochondrial inner membrane]

Literature

The enzymes, regulation, and genetics of bile acid synthesis Annu Rev Biochem, 2003