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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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Two FAPP molecules dimerize to form presqualene diphosphate

2 FAPP → PPi + PSQPP

Reactome
R-HSA-191405
Compartment
cytosol · endoplasmic reticulum membrane
Rhea
RHEA:22673

Inputs

Outputs

Catalysed by

  • squalene synthase [NAD(P)H] activity of FDFT:Mg2+ [endoplasmic reticulum membrane]EC 2.5.1.21

Literature

  1. Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis. J Biol Chem, 2000