Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol

IP6 + ATP → 5-PP-IP5 + ADP

Reactome: R-HSA-1855227
Compartment: cytosol
Rhea: RHEA:12794

Inputs

IP6CHEBI:58130, C6H6O24P6, cytosol
ATPCHEBI:30616, C10H12N5O13P3, cytosol

Outputs

5-PP-IP5CHEBI:58628, C6H6O27P7, cytosol
ADPCHEBI:456216, C10H12N5O10P2, cytosol

Catalysed by

inositol hexakisphosphate kinase activity of IP6K1/3 [cytosol]

IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol

Inputs

Outputs

Catalysed by

Literature