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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol

IP6 + ATP → 1-PP-IP5 + ADP

Reactome: R-HSA-1855216
Compartment: cytosol
Rhea: RHEA:37460

Inputs

IP6CHEBI:58130, C6H6O24P6, cytosol
ATPCHEBI:30616, C10H12N5O13P3, cytosol

Outputs

1-PP-IP5CHEBI:74946, C6H6O27P7, cytosol
ADPCHEBI:456216, C10H12N5O10P2, cytosol

Catalysed by

inositol hexakisphosphate kinase activity of PPIP5K1/2 [cytosol]

Literature