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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus

IP6 + ATP → 5-PP-IP5 + ADP

Reactome
R-HSA-1855207
Compartment
nucleoplasm
Rhea
RHEA:12794

Inputs

Outputs

Catalysed by

  • inositol hexakisphosphate kinase activity of IP6K1/2 [nucleoplasm]

Literature

  1. Identification and characterization of a novel inositol hexakisphosphate kinase J Biol Chem, 2001
  2. A conserved family of enzymes that phosphorylate inositol hexakisphosphate Science, 2007
  3. Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups Chem Biol, 2008