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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol

I(1,3,4)P3 + ATP → I(1,3,4,6)P4 + ADP + H+

Reactome
R-HSA-1855197
Compartment
cytosol
Rhea
RHEA:20941

Inputs

Outputs

Catalysed by

  • inositol-1,3,4-trisphosphate 6-kinase activity of ITPK1:Mg2+ [cytosol]EC 2.7.1.159

Literature

  1. Isolation of inositol 1,3,4-trisphosphate 5/6-kinase, cDNA cloning and expression of the recombinant enzyme J Biol Chem, 1996
  2. Multitasking in signal transduction by a promiscuous human Ins(3,4,5,6)P(4) 1-kinase/Ins(1,3,4)P(3) 5/6-kinase Biochem J, 2000