I(1,4,5)P3 transports from the cytosol to the nucleus
I(1,4,5)P3 → I(1,4,5)P3
- Reactome
- R-HSA-1855190
- Compartment
- cytosol · nucleoplasm
- Rhea
- None recorded
Inputs
- I(1,4,5)P3CHEBI:203600, C6H9O15P3, cytosol
Outputs
- I(1,4,5)P3CHEBI:203600, C6H9O15P3, nucleoplasm
Catalysed by
- narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
Literature
- The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells Biochem J, 2003
- The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization Biochem J, 2002