I(1,3,4,5)P4 transports from the cytosol to the nucleus
I(1,3,4,5)P4 → I(1,3,4,5)P4
- Reactome
- R-HSA-1855168
- Compartment
- cytosol · nucleoplasm
- Rhea
- None recorded
Inputs
- I(1,3,4,5)P4CHEBI:57895, C6H8O18P4, cytosol
Outputs
- I(1,3,4,5)P4CHEBI:57895, C6H8O18P4, nucleoplasm
Catalysed by
- narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
Literature
- The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells Biochem J, 2003
- The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization Biochem J, 2002