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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol

I1P + H2O → Ins + Pi

Reactome
R-HSA-1855154
Compartment
cytosol
Rhea
RHEA:27671

Inputs

Outputs

Catalysed by

  • inositol monophosphate 1-phosphatase activity of IMPA1/2 [cytosol]EC 3.1.3.25

Literature

  1. cDNA cloning of human and rat brain myo-inositol monophosphatase. Expression and characterization of the human recombinant enzyme Biochem J, 1992
  2. Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1 J Biol Chem, 2007