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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Reducing equivalents from beta-oxidation of fatty acids transfer to ETF

FADH2 + ETF:FAD → ETF:FADH2 + FAD

Reactome: R-HSA-169260
Compartment: mitochondrial matrix
Rhea: None recorded

Inputs

FADH2CHEBI:58307, C27H33N9O15P2, mitochondrial matrix
ETF:FADR-HSA-169267, mitochondrial matrix

Outputs

ETF:FADH2R-HSA-169268, mitochondrial matrix
FADCHEBI:57692, C27H30N9O15P2, mitochondrial matrix

Catalysed by

electron transfer activity of ETF:FAD [mitochondrial matrix]

Literature

Defects in mitochondrial beta-oxidation of fatty acids Curr. Opin. Lipidol., 1999