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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane

PI3P + ATP → PI(3,5)P2 + ADP

Reactome
R-HSA-1676134
Compartment
plasma membrane · cytosol
Rhea
RHEA:13609

Inputs

Outputs

Catalysed by

  • 1-phosphatidylinositol-3-phosphate 5-kinase activity of PIP5K1A/B [cytosol]EC 2.7.1.150

Literature

  1. Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate J Biol Chem, 1998