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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane

ATP + PI → ADP + PI4P

Reactome
R-HSA-1675974
Compartment
early endosome membrane · cytosol
Rhea
RHEA:19877

Inputs

Outputs

Catalysed by

  • 1-phosphatidylinositol 4-kinase activity of PI4K2A/2B [cytosol]EC 2.7.1.67

Literature

  1. Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments J Biol Chem, 2002