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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap

Data

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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane

ATP + PI → ADP + PI3P

Reactome: R-HSA-1675939
Compartment: early endosome membrane · cytosol
Rhea: RHEA:12709

Inputs

ATPCHEBI:30616, C10H12N5O13P3, cytosol
PICHEBI:57880, C11H16O13PR2, early endosome membrane

Outputs

ADPCHEBI:456216, C10H12N5O10P2, cytosol
PI3PCHEBI:58088, C11H15O16P2R2, early endosome membrane

Catalysed by

1-phosphatidylinositol-3-kinase activity of PIK3C2A/3 [cytosol]EC 2.7.1.137

Literature