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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

PI4P transports from the Golgi membrane to the plasma membrane

PI4P → PI4P

Reactome: R-HSA-1675815
Compartment: Golgi membrane · plasma membrane
Rhea: None recorded

Inputs

PI4PCHEBI:17526, C11H18O16P2R2, Golgi membrane

Outputs

PI4PCHEBI:17526, C11H18O16P2R2, plasma membrane

Literature

Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling Proc Natl Acad Sci U S A, 2010
FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P Nat Cell Biol, 2004
Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2) Biochem J, 2009