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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY

BET + HCYS → DMGLY + L-Met

Reactome
R-HSA-1614654
Compartment
cytosol
Rhea
RHEA:22337

Inputs

Outputs

Catalysed by

  • betaine-homocysteine S-methyltransferase activity of BHMT:Zn2+ tetramer [cytosol]EC 2.1.1.5

Literature

  1. Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: common gene sequence variation and functional characterization Mol Genet Metab, 2008