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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Cysteine is degraded to pyruvate and H2S

H2O + L-Cys → H+ + NH4+ + PYR + H2S

Reactome: R-HSA-1614614
Compartment: cytosol
Rhea: RHEA:24932

Inputs

H2OCHEBI:15377, H2O, cytosol
L-CysCHEBI:35235, C3H7NO2S, cytosol

Outputs

H+CHEBI:15378, H, cytosol
NH4+CHEBI:28938, H4N, cytosol
PYRCHEBI:15361, C3H3O3, cytosol
H2SCHEBI:29919, HS, cytosol

Catalysed by

carbon-sulfur lyase activity of PXLP-K212-CTH tetramer [cytosol]EC 4.4

Cysteine is degraded to pyruvate and H2S

Inputs

Outputs

Catalysed by

Literature