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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Excess homocysteine yields homolanthionine and H2S

2 HCYS → HLAN + H2S + H+

Reactome: R-HSA-1614567
Compartment: cytosol
Rhea: RHEA:68653

Inputs

2 HCYSCHEBI:58199, C4H9NO2S, cytosol

Outputs

HLANCHEBI:178194, C8H16N2O4S, cytosol
H2SCHEBI:29919, HS, cytosol
H+CHEBI:15378, H, cytosol

Catalysed by

carbon-sulfur lyase activity of PXLP-K212-CTH tetramer [cytosol]EC 4.4

Excess homocysteine yields homolanthionine and H2S

Inputs

Outputs

Catalysed by

Literature