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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

Sulfate is exported to the cytosol in exchange for dicarboxylate

MAL + SO4(2-) → MAL + SO4(2-)

Reactome: R-HSA-1614546
Compartment: mitochondrial inner membrane · cytosol · mitochondrial matrix
Rhea: RHEA:71615

Inputs

MALCHEBI:15589, C4H4O5, cytosol
SO4(2-)CHEBI:16189, O4S, mitochondrial matrix

Outputs

MALCHEBI:15589, C4H4O5, mitochondrial matrix
SO4(2-)CHEBI:16189, O4S, cytosol

Catalysed by

dicarboxylic acid transmembrane transporter activity of SLC25A10 [mitochondrial inner membrane]UniProt Q9UBX3

Literature

Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family Biochem J, 1999
The transport of sulphate and sulphite in rat liver mitochondria Biochem J, 1974