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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine

choloyl-CoA; chenodeoxycholoyl-CoA + Gly, TAU → bile salts + CoA-SH

Reactome
R-HSA-159431
Compartment
cytosol
Rhea
None recorded

Inputs

Outputs

Catalysed by

Literature

  1. Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase. J Biol Chem, 1994
  2. Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from human liver J Biol Chem, 1991
  3. Subcellular organization of bile acid amidation in human liver: a key issue in regulating the biosynthesis of bile salts J Lipid Res, 2000