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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

PG is converted to BMP

PG → BMP

Reactome: R-HSA-1483209
Compartment: late endosome membrane
Rhea: None recorded

Inputs

PGCHEBI:64716, C8H12O10PR2, late endosome membrane

Outputs

BMPCHEBI:60815, C10H23O8P, late endosome membrane

Literature

Transacylase formation of bis(monoacylglycerol)phosphate Biochim Biophys Acta, 1999
Biological Function of the Cellular Lipid BMP-BMP as a Key Activator for Cholesterol Sorting and Membrane Digestion Neurochem Res, 2010
Conversion of diphosphatidylglycerol to bis(monoacylglyceryl)phosphate by lysosomes J Lipid Res, 1978
De novo biosynthesis of the late endosome lipid, bis(monoacylglycero)phosphate J Lipid Res, 2007