PC is transphosphatidylated to PG by PLD1-4/6
PC + Glycerol → PG + Cho
- Reactome
- R-HSA-1483142
- Compartment
- endoplasmic reticulum membrane · cytosol
- Rhea
- None recorded
Inputs
- PCCHEBI:57643, C10H18NO8PR2, endoplasmic reticulum membrane
- GlycerolCHEBI:17754, C3H8O3, cytosol
Outputs
- PGCHEBI:64716, C8H12O10PR2, endoplasmic reticulum membrane
- ChoCHEBI:15354, C5H14NO, cytosol
Catalysed by
- D-type glycerophospholipase activity of PLD1-4/6 [endoplasmic reticulum membrane]EC 3.1.4.4
Literature
- Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family J Biol Chem, 1995
- Characterization of human PLD2 and the analysis of PLD isoform splice variants FASEB J, 1998
- A human homolog of the vaccinia virus HindIII K4L gene is a member of the phospholipase D superfamily Virus Res, 1997