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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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PI is exchanged with PC by PITPNB

PI:PITPNB + PC → PI + PC:PITPNB

Reactome
R-HSA-1483087
Compartment
Golgi membrane
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • phosphatidylcholine transfer activity of PI:PITPNB [Golgi membrane]

Literature

  1. Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells Traffic, 2008
  2. Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum J Cell Sci, 2010
  3. Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine J Biol Chem, 2001
  4. Structure of PITPbeta in complex with phosphatidylcholine: comparison of structure and lipid transfer to other PITP isoforms Biochemistry, 2005
  5. Structure of apo-phosphatidylinositol transfer protein alpha provides insight into membrane association EMBO J, 2002
  6. Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol Structure, 2004