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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

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Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

CDP-DAG is converted to PI by CDIPT

CDP-DAG + Ins → PI + CMP

Reactome: R-HSA-1482976
Compartment: endoplasmic reticulum membrane · cytosol
Rhea: RHEA:11580

Inputs

CDP-DAGCHEBI:58332, C14H17N3O15P2R2, endoplasmic reticulum membrane
InsCHEBI:17268, C6H12O6, cytosol

Outputs

PICHEBI:57880, C11H16O13PR2, endoplasmic reticulum membrane
CMPCHEBI:60377, C9H12N3O8P, cytosol

Catalysed by

CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity of CDIPT:Mg2+/Mn2+ [endoplasmic reticulum membrane]EC 2.7.8.11

Literature

The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content J Biol Chem, 1997