CDP-ETA and DAG are converted to PE by CEPT1/EPT1
DAG + CDP-ETA → PE + CMP
- Reactome
- R-HSA-1482962
- Compartment
- endoplasmic reticulum membrane · cytosol
- Rhea
- None recorded
Inputs
- DAGCHEBI:17815, C5H6O5R2, endoplasmic reticulum membrane
- CDP-ETACHEBI:57876, C11H19N4O11P2, cytosol
Outputs
- PECHEBI:57613, C7H12NO8PR2, endoplasmic reticulum membrane
- CMPCHEBI:60377, C9H12N3O8P, cytosol
Catalysed by
- ethanolaminephosphotransferase activity of CEPT1/EPT1 [endoplasmic reticulum membrane]EC 2.7.8.1
Literature
- Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine Biochem J, 1999
- Cloning, genomic organization, and characterization of a human cholinephosphotransferase J Biol Chem, 2000
- PC and PE synthesis: mixed micellar analysis of the cholinephosphotransferase and ethanolaminephosphotransferase activities of human choline/ethanolamine phosphotransferase 1 (CEPT1) Lipids, 2002
- The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity Mol Biol Cell, 2002
- Identification and characterization of human ethanolaminephosphotransferase1 J Lipid Res, 2007