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Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

CDP-DAG is converted to PGP by PGS1

CDP-DAG + G3P → PGP + CMP

Reactome: R-HSA-1482939
Compartment: mitochondrial inner membrane · mitochondrial matrix
Rhea: RHEA:12593

Inputs

CDP-DAGCHEBI:58332, C14H17N3O15P2R2, mitochondrial inner membrane
G3PCHEBI:57597, C3H7O6P, mitochondrial matrix

Outputs

PGPCHEBI:60110, C8H11O13P2R2, mitochondrial inner membrane
CMPCHEBI:60377, C9H12N3O8P, mitochondrial matrix

Catalysed by

CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity of PGS1 [mitochondrial inner membrane]EC 2.7.8.5; UniProt Q32NB8

Literature

Complete sequencing and characterization of 21,243 full-length human cDNAs Nat Genet, 2004