2-acyl LPS is acylated to PS by LPSAT

2-acyl LPS + acyl-CoA → PS + CoA-SH

Reactome

R-HSA-1482691

Compartment

endoplasmic reticulum membrane · cytosol

Rhea

None recorded

Catalysed by

• 2-acylglycerol-3-phosphate O-acyltransferase activity of LPSAT [endoplasmic reticulum membrane]EC 2.3.1.52

Literature

1. Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity Proc Natl Acad Sci U S A, 2008
2. Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils J Biol Chem, 2008
3. Molecular identification of a novel mammalian brain isoform of acyl-CoA:lysophospholipid acyltransferase with prominent ethanolamine lysophospholipid acylating activity, LPEAT2 J Biol Chem, 2008