1-acyl LPG is acylated to PG by LPGAT

1-acyl LPG + acyl-CoA → PG + CoA-SH

Reactome

R-HSA-1482539

Compartment

endoplasmic reticulum membrane · cytosol

Rhea

None recorded

Catalysed by

• 1-acylglycerol-3-phosphate O-acyltransferase activity of LPGAT [endoplasmic reticulum membrane]EC 2.3.1.51

Literature

1. Molecular identification of a novel mammalian brain isoform of acyl-CoA:lysophospholipid acyltransferase with prominent ethanolamine lysophospholipid acylating activity, LPEAT2 J Biol Chem, 2008
2. Cloning and characterization a novel human 1-acyl-sn-glycerol-3-phosphate acyltransferase gene AGPAT7 DNA Seq, 2005
3. Identification and characterization of a gene encoding human LPGAT1, an endoplasmic reticulum-associated lysophosphatidylglycerol acyltransferase J Biol Chem, 2004
4. Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production J Biol Chem, 2006
5. Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells Proc Natl Acad Sci U S A, 2006