Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

ADP + ADP AMP + ATP [AK2]

2 ADP → AMP + ATP

Reactome: R-HSA-110144
Compartment: cytosol · mitochondrial intermembrane space
Rhea: RHEA:12975

Inputs

2 ADPCHEBI:456216, C10H12N5O10P2, cytosol

Outputs

AMPCHEBI:456215, C10H12N5O7P, cytosol
ATPCHEBI:30616, C10H12N5O13P3, cytosol

Catalysed by

AMP kinase activity of AK2 [mitochondrial intermembrane space]EC 2.7.4.3; UniProt P54819

ADP + ADP AMP + ATP [AK2]

Inputs

Outputs

Catalysed by

Literature