Loading the map…

Human metabolism

Reactome's human metabolism drawn as one network. Each molecule has one home node; widely shared molecules also appear as dashed copies in other territories, linked from their details. .

Territories

Select a territory to bring it forward.

Reading the map

Metabolite; its structure appears as you zoom in
Reaction, arrow toward the product
Cofactors and co-substrates are written beside the reaction when you zoom in
Dashed ring: a copy of a widely shared molecule or cofactor in another territory or pathway
Compartment transfer of the molecule it is linked to
Binding, release or complex event; its proteins are named in its details
Outline: reactions mostly in the mitochondrion

Arrows follow Reactome's curated reaction direction.

dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA

4-cis-decenoyl-CoA + FAD → 2-trans-4-cis-decadienoyl-CoA + FADH2

Reactome: R-HSA-109341
Compartment: mitochondrial matrix
Rhea: None recorded

Inputs

4-cis-decenoyl-CoACHEBI:29140, C31H52N7O17P3S, mitochondrial matrix
FADCHEBI:57692, C27H30N9O15P2, mitochondrial matrix

Outputs

2-trans-4-cis-decadienoyl-CoACHEBI:137593, C31H46N7O17P3S, mitochondrial matrix
FADH2CHEBI:58307, C27H33N9O15P2, mitochondrial matrix

Catalysed by

acyl-CoA dehydrogenase activity of ACADM tetramer [mitochondrial matrix]EC 1.3.99.3