Source assertion

PDBe/SIFTS maps PDB 6H38 to UniProt P43166 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:6H38:UNIPROT:P43166
Subject dossier: ca7
Source chain: uniprot + pdbe
Upstream record: 6H38
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: In this release

Experimental structure

The crystal structure of human carbonic anhydrase VII in complex with 4-[(4-fluorophenyl)methyl]-1-piperazinyl]benzenesulfonamide.

PDB ID: 6H38
Experimental method: X-ray diffraction
Resolution: %!f(*float64=0x24b06afffe60) Å
SIFTS identifier: CAH7_HUMAN
Deposited: 20180717
Released / revised: 20181219 / 20241009

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	99.0%	100.0%	1–264

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A / A	Carbonic anhydrase 7polypeptide(L)	274 residues	C183S, C217S	Genetically manipulated

Reading this structure

This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.

Snapshot provenance

Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:32Z	`raw/uniprot/entries/P43166.json`	`dc0ec23dc5d7dfcf4737e905d75df89f664cdb3e05519fcfef79fbaf218da84f`	Open exact source
2026-07-14T09:21:59Z	`raw/pdbe/mappings/6h38.json`	`009c8283ebc16573ffdf143a58d729d07ca46eb510ec6b899bcbeb10c5ca1d78`	Open exact source
2026-07-14T09:22:17Z	`raw/pdbe/summary/chunk-04.json`	`9993579d3f578cc0a0be921bfc6aa7a181fb8a074c2cd246c08a1da9b7d92dfc`	Open exact source
2026-07-14T09:22:18Z	`raw/pdbe/experiment/chunk-04.json`	`9fbf526866182ab693088d3c63735d5e62302d743c66532fd0163f0cb378a25b`	Open exact source
2026-07-14T09:22:19Z	`raw/pdbe/molecules/chunk-04.json`	`3e3b75bb7fa19acefd58e3b24f2d7e54feb541eeb253bea88d1e20ba0ccd936c`	Open exact source