Source assertion
PDBe/SIFTS maps PDB 5KU6 to UniProt P22748 with chain-level identity and coverage retained.
Experimental structure
Crystal structure for the complex of human carbonic anhydrase IV and methazolamide
- PDB ID
5KU6- Experimental method
- X-ray diffraction
- Resolution
- %!f(*float64=0x24b06afff810) Å
- SIFTS identifier
CAH4_HUMAN- Deposited
- 20160712
- Released / revised
- 20170726 / 20241023
Chain-level mapping
| Entity | Chain | Structural asym | Identity | Coverage | UniProt range |
|---|---|---|---|---|---|
| 1 | A | A | 100.0% | 90.5% | 19–284 |
| 1 | B | B | 100.0% | 90.5% | 19–284 |
| 1 | C | C | 100.0% | 90.5% | 19–284 |
| 1 | D | D | 100.0% | 90.5% | 19–284 |
Experimental constructs
| Entity | Chains / asym IDs | Molecule | Length | Mutation flag | Preparation |
|---|---|---|---|---|---|
| 1 | A, B, C, D / A, B, C, D | Carbonic anhydrase 4polypeptide(L) | 266 residues | not reported by the source | Genetically manipulated |
Reading this structure
This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.
Snapshot provenance
Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.
| Retrieved | Snapshot | SHA-256 | Upstream request |
|---|---|---|---|
| 2026-07-14T09:21:32Z | raw/uniprot/entries/P22748.json | 28fa76c5a216b9356479d42199f709dd46e662172f2872078a5491cfe2c618f1 | Open exact source |
| 2026-07-14T09:21:53Z | raw/pdbe/mappings/5ku6.json | 6a4807ddebf1fff22928ccad710da023c52adf2c5d9ca945ff6a0fc6a00d8df8 | Open exact source |
| 2026-07-14T09:22:16Z | raw/pdbe/summary/chunk-03.json | d318ed911ff2a8e3f25986a39c37baa2a3bb13c1d2a75d036924ca34ffa2b9cb | Open exact source |
| 2026-07-14T09:22:16Z | raw/pdbe/experiment/chunk-03.json | 8bbfae15de944b1cacdf21ee7a42caf9f09149a49b6fdf48f69df854b06973c9 | Open exact source |
| 2026-07-14T09:22:17Z | raw/pdbe/molecules/chunk-03.json | e94951408bdc68a6d0767211c754ae03dc74c4cf253ad3a7626c02d4aaba5eeb | Open exact source |