Source assertion
PDBe/SIFTS maps PDB 3FW3 to UniProt P22748 with chain-level identity and coverage retained.
Experimental structure
Crystal Structure of soluble domain of CA4 in complex with Dorzolamide
- PDB ID
3FW3- Experimental method
- X-ray diffraction
- Resolution
- %!f(*float64=0x24b06affe360) Å
- SIFTS identifier
CAH4_HUMAN- Deposited
- 20090116
- Released / revised
- 20091201 / 20241106
Chain-level mapping
| Entity | Chain | Structural asym | Identity | Coverage | UniProt range |
|---|---|---|---|---|---|
| 1 | A | A | 100.0% | 90.5% | 19–284 |
| 1 | B | B | 100.0% | 90.5% | 19–284 |
Experimental constructs
| Entity | Chains / asym IDs | Molecule | Length | Mutation flag | Preparation |
|---|---|---|---|---|---|
| 1 | A, B / A, B | Carbonic anhydrase 4polypeptide(L) | 266 residues | not reported by the source | Genetically manipulated |
Reading this structure
This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.
Snapshot provenance
Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.
| Retrieved | Snapshot | SHA-256 | Upstream request |
|---|---|---|---|
| 2026-07-14T09:21:32Z | raw/uniprot/entries/P22748.json | 28fa76c5a216b9356479d42199f709dd46e662172f2872078a5491cfe2c618f1 | Open exact source |
| 2026-07-14T09:21:50Z | raw/pdbe/mappings/3fw3.json | 4ba26449fccaf51ec39ede553b0f6a499d874417bd8a58ce7da9eb7316b32b4a | Open exact source |
| 2026-07-14T09:22:14Z | raw/pdbe/summary/chunk-02.json | 79ac3fb4e9e30c8c858b4d8ed8bbe6f85e8e0d0e3630627a999691f40a3d330d | Open exact source |
| 2026-07-14T09:22:14Z | raw/pdbe/experiment/chunk-02.json | e42f681713cd9cdce851cc48738b3c6e0f0c075d0006a640c484bcab84561898 | Open exact source |
| 2026-07-14T09:22:15Z | raw/pdbe/molecules/chunk-02.json | 27833f4d4cb9a9bfcb110f6e551fe2a5ccef01ccea4dda947132af6c51bd66e6 | Open exact source |