Source assertion

PDBe/SIFTS maps PDB 3F7B to UniProt P22748 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:3F7B:UNIPROT:P22748
Subject dossier: ca4
Source chain: uniprot + pdbe
Upstream record: 3F7B
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: In this release

Experimental structure

Crystal Structure of soluble domain of CA4 in complex with small molecule.

PDB ID: 3F7B
Experimental method: X-ray diffraction
Resolution: %!f(*float64=0x2eca05fee390) Å
SIFTS identifier: CAH4_HUMAN
Deposited: 20081107
Released / revised: 20090922 / 20241113

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	100.0%	90.5%	19–284
1	`B`	`B`	100.0%	90.5%	19–284

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A, B / A, B	Carbonic anhydrase 4polypeptide(L)	266 residues	not reported by the source	Genetically manipulated

Reading this structure

This is an experimentally determined structure, not a predicted model. A co-crystallised ligand, if any, does not by itself show binding affinity. The structure says nothing about kinetics, pathway rate or metabolic flux.

Snapshot provenance

Each row is a source snapshot this record was built from: when it was retrieved, its path and SHA-256 digest, and the exact request. The snapshot files stay with the build and are not served here. These rows document this record; they are not general citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:32Z	`raw/uniprot/entries/P22748.json`	`28fa76c5a216b9356479d42199f709dd46e662172f2872078a5491cfe2c618f1`	Open exact source
2026-07-14T09:21:51Z	`raw/pdbe/mappings/3f7b.json`	`230f2801d13372ec379ca3ae5eb3f03693dcfce9b1534bb17bb3f94c4f809cf5`	Open exact source
2026-07-14T09:22:14Z	`raw/pdbe/summary/chunk-02.json`	`79ac3fb4e9e30c8c858b4d8ed8bbe6f85e8e0d0e3630627a999691f40a3d330d`	Open exact source
2026-07-14T09:22:14Z	`raw/pdbe/experiment/chunk-02.json`	`e42f681713cd9cdce851cc48738b3c6e0f0c075d0006a640c484bcab84561898`	Open exact source
2026-07-14T09:22:15Z	`raw/pdbe/molecules/chunk-02.json`	`27833f4d4cb9a9bfcb110f6e551fe2a5ccef01ccea4dda947132af6c51bd66e6`	Open exact source