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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
Data
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TP53 binds CPS1 gene

TP53 Tetramer + CPS1 gene → TP53 tetramer:CPS1 gene

Reactome
R-HSA-9959860
Compartment
nucleoplasm
Rhea
None recorded

Inputs

Outputs

Catalysed by

  • DNA-binding transcription repressor activity of TP53 Tetramer [nucleoplasm]

Literature

  1. p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis Nature, 2019
  2. Polyamines in cancer: integrating organismal metabolism and antitumour immunity Nat Rev Cancer, 2022