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DraconiticBiochemistryBiomolecules · Catabolism · Biosynthesis · MetabolismMap
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OTC precursor is targeted to the mitochondrial matrix and processed

OTC precursor → OTC trimer

Reactome
R-HSA-9956502
Compartment
cytosol · mitochondrial matrix
Rhea
None recorded

Inputs

Outputs

Literature

  1. Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase. Science, 1984
  2. Mitochondrial Machineries for Protein Import and Assembly Annu. Rev. Biochem., 2017
  3. 1.85-A resolution crystal structure of human ornithine transcarbamoylase complexed with N-phosphonacetyl-L-ornithine. Catalytic mechanism and correlation with inherited deficiency J Biol Chem, 1998
  4. Crystal structure of human ornithine transcarbamylase complexed with carbamoyl phosphate and L-norvaline at 1.9 A resolution Proteins, 2000