OTC precursor is targeted to the mitochondrial matrix and processed
OTC precursor → OTC trimer
- Reactome
- R-HSA-9956502
- Compartment
- cytosol · mitochondrial matrix
- Rhea
- None recorded
Inputs
- OTC precursorR-HSA-9956408, cytosol
Outputs
- OTC trimerR-HSA-70558, mitochondrial matrix
Literature
- Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase. Science, 1984
- Mitochondrial Machineries for Protein Import and Assembly Annu. Rev. Biochem., 2017
- 1.85-A resolution crystal structure of human ornithine transcarbamoylase complexed with N-phosphonacetyl-L-ornithine. Catalytic mechanism and correlation with inherited deficiency J Biol Chem, 1998
- Crystal structure of human ornithine transcarbamylase complexed with carbamoyl phosphate and L-norvaline at 1.9 A resolution Proteins, 2000